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The Friendly Neighborhood Spider-Man swings into Marvel Mystic Mayhem with his iconic webs and superhuman strength. In this guide, we’ll cover everything you need to know about Spider-Man in Marvel Mystic Mayhem.
Spider-Man Overview
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Class | Controller |
Type | Concussive |
Spider-Man is a top-tier Controller in Marvel Mystic Mayhem. His kit allows him to buff teammates, debuff enemies, and deal respectable damage at the same time. His overall health and defense are moderate. However, he cannot function as a solo Controller due to the lack of healing abilities. He performs best when paired with another Controller and synergizes well with other debuff-focused characters.
Spider-Man Skills
Skill | Type | Description |
Friendly Neighbor | Dash / Buff | Moves to the target location and reduces the Mana costs of Spider-Man and his adjacent allies' next Skills by 1. Spidey Slam deals 105% more DMG for the next 10s. |
Web Spinner | Debuff / Physical Damage | Deals 180% of Spider-Man's ATK as Physical DMG to enemies in the target area, applying Webbed for 85. Webbed: Reduces Attack Speed by 50%. |
Spider-Versus | Physical Damage (Ultimate) | Deals 480% of Spider-Man's ATK as Physical DMG to an enemy and 240% of Spider-Man's ATK as Physical DMG to enemies adjacent to the target. |
Spidey Slam | Passive | After an ally attacks Webbed enemies with a Skill or Ultimate Move, Spider-Man performs a follow-up attack that deals Physical DMG to one of the enemies. |
How to Play Spider-Man in Mystic Mayhem
Spider-Man is a Controller who also functions as a hybrid Striker. His skills deal decent damage while simultaneously applying debuffs to enemies. He can also buff allies while maintaining mobility across the battlefield.
- With average defensive stats, it’s best to position him just behind the Defender or Fighter.
- As a secondary Controller, he should ideally be placed in front of the main support to strike a balance between safety and utility.

The Friendly Neighbor skill is an excellent mobility and support ability. Use it to swing toward allies who would benefit most from Mana cost reduction, such as Scarlet Witch or Armor.
Web Spinner is a strong damaging skill that also applies Webbing to enemies within the AoE, reducing their attack speed by a significant 50%. This skill pairs well with heroes who also apply and rely on debuffs, such as Storm or Mister Negative.

What makes it even better is that Spider-Man performs a follow-up attack whenever an ally uses a skill on a webbed enemy. This effect continues to trigger as long as the enemy remains webbed, making it a powerful tool for sustained damage and synergy with skill-heavy allies.

Spider-Man’s Ultimate deals heavy damage to a target and adjacent enemies, making it a valuable tool against bosses or tightly grouped foes. To maximize its effectiveness, it’s best to equip Artifacts that boost Ultimate energy regeneration, allowing you to unleash his devastating Ultimate more frequently throughout the battle.
Best Team Composition
-Guide coming soon-
Best Artifacts for Spider-Man
-Guide coming soon-
Best Highlight for Spider-Man
-Guide coming soon-