Genshin Impact: Quenepa Berry Route & Farming Guide

There are a total of 81 Quenepa Berry in Natlan, not including the one from the shop and the one-time farm. Keep in mind that few of the Quenepa Berry are located inside a locked area and you need to complete certain quests to be able to unlock it.
In this guide, there will be a link to the official interactive map. So you can mark your pins (to see which you have already collected them) and follow along the route.

Teyvat Interactive Map

24 Quenepa Berry in Tequemecan Valley

For the second route (the one with the underground berry), you can only get them after you start a quest [Ripe For Trouble]. This quest will unlock a hidden area inside a cave with lava in it. You only have to start it because these Berries are close to the surface and even closer to the waypoint underground.

How to Start Ripe For Trouble Quest

Teleport to Statue of the Seven north of the "Scions of the Canopy" and head east toward the camp in between the S7 and Weapon Domain. At the camp, you can pick up a piece of paper on top of the box as it's the item you need to start the quest: Green-Edged Paper Slip.

Now that you have the paper slip, teleport to the Weapon Domain and head north toward a canyon. There's an NPC just below the canyon and you can talk to her to start the Ripe For Trouble quest. After that, keep following the quest navigation to head further inside the cave until you reach an open area with huge tree roots.
You can see the whole guide here: Ripe For Trouble Quest Guide

57 Quenepa Berry in Ancestral Temple and Teticpac Peak

Lots of teleporting back to the waypoint here because the Berries here are many but pretty scattered from each other. Thankfully all of them are near the waypoints.

10 Quenepa Berry in Tequemecan Valley

Important: Remember that the Berries in this route are just one-time! Meaning after you get these Berries, you won't be able to farm them again. All of these are not near their plants but scattered around on the path and on top of a tree.

9 Quenepa Berry inside a Treasure Chest

Go to the top of a waypoint in Teticpac Peak and go to the northeast a little bit to find a group of Hilichurls and a treasure chest. Defeat them and unlock the treasure chest for 9 Quenepa Berry. Same as before, this is a one-time thing.

5 Quenepa Berry in Shop

Talk to Cintli (Shop NPC) at the Stadium of the Sacred Flame and you can buy 5 Quenepa Berry.